APIDRA PI PDF

PI & CMI Trade Names and Active Ingredients containing insulin glulisine. 1 Documents available. Need more information on a Apidra, CMIPI, Insulin glulisine. PI & CMI Trade Names and Active Ingredients containing insulin. 42 Documents Actrapid, PI, Insulin – human (human insulin) Apidra, CMIPI, Insulin glulisine. Apidra PI MKT. #v Page 1. PRODUCT INFORMATION. APIDRA APIDRA [insulin glulisine injection {rDNA origin}] is a recombinant human insulin .

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There is a theoretical concern that they could increase the risk of tumor development due to altered binding characteristics to insulin and insulin-like growth factor IGF -1 receptors caused by the structural changes made to the native insulin molecule. This can be given by a relative, friend, workmate or carer who knows how to give it.

Your doctor may increase or decrease the dose, depending on your blood apidrw levels. There have been limited studies in children evaluating pharmacokinetics and pharmacodynamics of glulisine. Draw air into a U insulin syringe equal to the dose of cloudy NPH insulin you are using.

Tolerability Flexibility of administration In ip, use of rapid-acting insulin analogs gives greater flexibility for the timing of injections, especially important for children and teenagers. Glulisine versus aspart There were no trials comparing the efficacy of glulisine with aspart in pediatric patients. Rapid apodra long-acting insulin analogues as an aproach to improve insulin therapy: Only mix Apidra with another insulin if your doctor has instructed you to do so.

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No specific studies have addressed quality of life QoL in patients on glulisine. Tell your doctor if you drink alcohol. Unlike the other rapid-acting insulin analogs, the oligomeric molecules of glulisine are apidrz without the addition of zinc, presumably because of the unaltered proline at position B28 thus allowing dimerization. Side effects Tell your doctor, pharmacist or diabetes educator as soon as possible if you do not feel well while you are using Apidra.

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Level 8, 56 Cawley Street. Choose a site for injection. A small crossover trial of 10 children and 10 adolescent patients with type 1 diabetes comparing RHI and glulisine found no severe hypoglycemic events. Lipodystrophy and weight gain can each occur in spidra subjects on long-term glulisine therapy.

Apidra –

Warnings and Precautions Insulin pens, needles, or syringes must never be shared between patients. Ask your doctor, pharmacist or diabetes educator for help.

The above list includes the more common side effects of your medicine. Inject the full dose of Apidra, or Apidra mixed with NPH insulin, by pushing the plunger as far as it will go.

The role of insulin glulisine to improve glycemic control in children with diabetes mellitus

The risk of hypoglycaemia is increased if you:. If you are experiencing low blood sugar levels hypoglycaemia – a “hypo”.

Health-related quality-of-life results from multinational clinical trials of insulin lispro: The approach to diabetes management is complex, and hypoglycemia arising from attempts to achieve normoglycemia or near-normoglycemia is understandably feared by aoidra, parents, and clinicians. If you are not sure whether you should start using this medicine, talk to your doctor.

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This is useful in young children, in whom it may be difficult to accurately predict carbohydrate intake. Certain heart medications, especially beta-blockers, may mask the symptoms of hypoglycaemia.

Fast-Acting, Mealtime Insulin | Apidra® (insulin glulisine [rDNA origin] injection)

Do not allow to freeze. Apidra is supplied in New Zealand by:. Monomers, dimmers, and hexamers In solution, insulin molecules exist in equilibrium between monomers, dimers, tetramers, hexamers, and higher-order aggregates. Rates of hypoglyemia are similar to rates with other rapid-acting analogs. If you have an allergy to:. Tell your apira, pharmacist or diabetes educator if you are travelling. Visit your apivra for regular checks of your eyes, feet, kidneys, heart, circulation, blood and blood pressure.

If not treated quickly, the ;i symptoms of hypoglycaemia may progress to loss of co-ordination, slurred speech, confusion, loss of consciousness and seizures. Illness, especially with nausea and vomiting, may cause your insulin needs to change. The most common side effect when using insulin is low blood sugar levels hypoglycaemia – a “hypo”. Always check the insulin label on the SoloStar pen, cartridge or vial before each injection to make sure you are using the right insulin.